Policosanol Clinical Trials Confirm that this All natural product made from sugar cane is superior.

Policosanol Clinical Trials Confirm its Superiority to Statin Drugs.

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  • Gene Millen, Author - Revised 5/11/15

    Gene Millen, Heart Health Coach

    I'm Gene Millen, your host on this website with my wife Bernie. In 1990 a heart surgeon sawed open my chest and revised the plumbing in my chest by bypassing six clogged heart arteries.

    A six way heart bypass isn't a record...but it did get my attention...and caused me to make a dramatic change in my heart health priorities.

    Recent Policosanol Clinical Trials

    Wikipedia indicates that policosanol clinical trials have shown mixed results. During the thirteen years that we have used and provided Vital Life Nutritionals Policosanol to our customers we have received many testimonials that it is improving cholesterol. See below.

    Published studies have come to conflicting conclusions regarding the efficacy of policosanol in lowering LDL (i.e., "bad cholesterol") or raising HDL (i.e., "good cholesterol").,[5][6][7] despite a number of studies funded by the Cuban government, which produces and markets the drug.[8] Older independent clinical trials found no evidence of the efficacy of policosanol,[5] while more recent studies have found effect.[9][10]

    In a report in New Hope Natural Media,Policosanol was shown shown to be more effective than Zocor and other statin drugs.

    "In a six-month policosanol clinical trial, 10 mg per day of Policosanol reduced total cholesterol by 16% and LDL cholesterol by 24%, and increased HDL cholesterol by 29%."

    Double Blind Study Comparing Policosanol to Statin Drugs

    In several policosanol statin drugs studies the results have shown this natural suplement derived from sugar cane to be more effective than Lovastatin (MevacorĀ®), pravastatin.

    Although policosanol and ZOCOR were found to be equally effective in lowering cholesterol during an eight week study policosanol also significantly increased HDL-cholesterol levels and Zocor DID NOT!
    This is significant, as HDL cholesterol (the good stuff) lowers the risk of heart attack and strokes!

    Pub Med Policosanol Clinical Studies Confirm Benefits.

    Long-term studies (52 and 104 weeks) with type 2 hypercholesterolemic patients showed that 5 mg twice daily lowered LDL cholesterol by 27.5% and 24.8%, lowered total cholesterol by 16.3% and 18.3%, and raised HDL cholesterol by 25.9% and 11.2%, respectively (p for all the above).[13,14] These four studies demonstrated that maximum LDL and total cholesterol reductions occur after six to eight weeks of policosanol use, whereas increases in HDL cholesterol require several months of therapy.

    A 12-week randomized clinical trial involving 29 patients with hypercholesterolemia and type 2 diabetes mellitus who were taking 5 mg of policosanol twice daily yielded similar results: LDL and total cholesterol were lowered 21.7% and 16.9%, respectively.[15]

    A larger randomized clinical trial involving 244 postmenopausal women with familial hypercholesterolemia found that, in successive groups receiving 12-week regimens of 5 and 10 mg/day, policosanol lowered LDL cholesterol by 17.7% and 25.% and total cholesterol by 12.6% and 16.7%, respectively.[16] In addition, their HDL cholesterol levels increased by 16.5% and 29.3%, respectively.

    A randomized clinical trial of 437 patients with familial hypercholesterolemia and more than two additional risk factors for coronary artery disease (CAD) received 5 mg/day of policosanol or placebo for 12 weeks, then 5 mg twice daily for an additional 12 weeks. The 5- and 10-mg policosanol regimens reduced LDL cholesterol by 18.2% and 25.6% and total cholesterol by 13.0% and 17.4%, respectively Patients' HDL cholesterol levels increased by 15.5% and 28.4%, respectively respectively.[17]

    A subsequent, 24-week randomized clinical trial by the same authors, involving 179 elderly patients (ages 60-78 years) with familial hypercholesterolemia and at high risk for CAD, found that successive 12-week daily doses of 5 mg, then 10 mg, significantly reduced patients' LDL cholesterol by 16.9% and 24.4% and total cholesterol by 12.8% and 16.2%, respectively [18] HDL cholesterol levels increased by 14.6% and 29.1%.

    Comparative policosanol clinical trials for treating hypercholesterolemia.

    Fifty-three patients with hypercholesterolemia and type 2 diabetes mellitus were randomized to receive either 10 mg of policosanol or 20 mg of lovastatin daily for 12 weeks.[19] Similar results were obtained with each group; policosanol lowered LDL and total cholesterol by 20.4% and 14.2%, respectively, from base line, while lovastatin lowered LDL and total cholesterol by 16.8% and 14.0% , respectively, from base line. Policosanol increased HDL cholesterol levels by 7.5% , and lovastatin lowered HDL cholesterol by 2.8% (not significant).

    Sixty-eight elderly (60-80 years old) patients with familial hypercholesterolemia and multiple risk factors for CAD were randomized to take policosanol or pravastatin 10 mg daily for eight weeks.[20] Again, similar results were obtained with each group; policosanol lowered LDL and total cholesterol by 19.3% and 13.9% from base line, respectively, while pravastatin lowered LDL and total cholesterol by 15.6% and 11.8% from base line, respectively.

    Another eight-week trial of 53 elderly patients with hypercholesterolemia compared the effectiveness of 5 mg of policosanol twice daily with 5 mg of simvastatin twice daily.[21] In the policosanol group, LDL and total cholesterol were lowered by 17.9% and 14.7%, respectively, whereas LDL and total cholesterol were lowered by 19.8% and 15.2%, respectively, in the simvastatin group for all groups).

    A Natural Medicine Physician Recommends Policosanol

    Dr. Michael MurrayDr. Michael Murray, author of Encyclopedia of Natural Medicine, one of the most renowned doctors of natural medicine says;

    "In a 1997 head-to-head study policosanol was compared with statin drugs lovastatin (Mevacor), simvastatin (Zocor) and pravastatin (Pravachol) Policosanol and ZOCOR were found to be equally effective in lowering cholesterol during an eight week study...but policosanol also significantly increased HDL-cholesterol levels and Zocor did not."

    In the studies Policosanol produced cholesterol-lowering effects within the first 6-8 weeks of use. At a daily dosage of 10-20 mg of policosanol at night, LDL cholesterol levels typically dropped by 20 to 25% within the first six months of therapy.
    At a dosage of 20 mg, LDL levels typically drop by 25-30%.
    HDL cholesterol levels typically increase by 15 to 25% after only two months of use.
    The combined LDL reduction and HDL increase can produce dramatic improvements in the LDL to HDL ratio, which lowers risk of a heart attack or stroke!

    Summary of Why Policosanol is Superior to the statin drug prescriptions.

    The number one reason is that it is a natural product derived from sugar cane that has been shown in numerous studies to be free of side effects.

    It has been shown to improve cholesterol as well or better than cholesterol-lowering drugs, without side effects such as liver dysfunction and muscle atrophy.

    Safety has been proven in clinical trials, and it has been safely used by millions of people in the U.S. and other countries.
    Recent clinical research has also shown additional benefits, including improving the control of blood sugar among people with diabetes, and reducing inflammation.The latest research shows that these are key risks that can lead to a heart attack.

    All Policosanol is Not Created Equal!

    In a policosanol online comparison study conducted by ConsumerLab four of seven policosanol products tested contained only 23% to 78% of the amount listed on the label.

    The original policosanol comparison studies were conducted with policosanol derived from sugar cane. It's wise to avoid policosanol made with bees wax, rice wax or other plant waxes as many are not as effective as the sugar cane formulas.

    The University of Kansas Hospital "Natural Pharmacist" website reports, "There is reason for concern that policosanol products made with bees wax may not be effective."

    If quality is important to you be certain that the manufacturer of the supplement meets the Good Manufacturing Practices standards. This insures you that what you see on the label is actually in the bottle!

    Vital Life Nutritionals and Policosanol Statin Drugs.

    For many years Vital Life Nutritionals Policosanol Extra Strength supplements have been our best selling solution to improving cholesterol.

    We only recommend the best heart supplements that we can find...ones that we and/or our family and friends personally use.

    Vital Life Nutritionals LogoThe Vital Life Nutritionals Difference

    Vital Life Nutritionals are manufactured by a family owned and operated nutritional company celebrating 90 years of promoting natural health and wellness.
    Vital Life Nutritionals Policosanol is extracted from sugar cane and is the same formula used in the clinical research studies.
    Only the finest ingredients are used and you never have to worry about how fresh our products are as each container has a user-friendly Best By date.
    Our products meet stringent FDA regulations. This is noteworthy, as most vitamin, mineral and herbal products do not have the oversight of the FDA.
    GMP Seal All Vital Life Nutritional products have received the highest rating in the GMP (Good Manufacturing Practices) program.
    You are guaranteed that what is on the label is inside the bottle. A large number of supplements do not meet this common sense test.
    Not only is our product superior but out pricing is excellent. Since we do not spend large sums for advertising the Vital Life Nutritionals brand we pass the savings along to you!
    If you don't get the results you expect from any of our products (which is rare) I'll give you a no hassle refund. You have the Millen's Personal Money Back Guarantee of Satisfaction!
    We are Independent Business Owners who have a powerful incentive to keep you satisfied. Our reputation depends on it!

    Edith's Policosanol Statin Drugs Experience.

    "My cholesterol was 397 and my doctor wanted to put me on Lipitor but I was afraid of the side effects. Gene gave me the research information on policosanol for my doctor to review and although he was somewhat skeptical he gave me the go ahead to give it a try.
    When I got my first follow up test after 8 weeks total cholesterol had dropped to 240. But the best news is that my HDL cholesterol was up which improved my ratio from 7 to 4.3 which is very good.
    I am elated and my doctor was pleased and I think a little bit surprised. He said "Keep on doing what you're doing." Edith

    Janelle's Policosanol Statin Drugs Story.

    "When the results of my lipid panel came back in the spring of 2001, my triglycerides were sky high (1723) and my HDL so low (8) that I was frightened enough to try any solution the doctor suggested.
    "A combination of a low-fat, low-carbohydrate diet, exercise and the use of high doses of niacin, brought the triglycerides down to a reasonable level; however, nothing seemed to budge the low HDL level to much above 18.
    "When we moved out of state, my new doctor insisted that I try a combination of niacin and simvastatin to address what he thought were "unacceptable" numbers. In 2024 I finally caved and agreed to the statin combo drug.

    Within a year I was unable to walk up and down stairs and couldn't lift myself from a sitting position without holding on to something.
    "I immediately stopped the statin/niacin (against the doctor's advice), and I began in earnest scouring the internet for alternative solutions to what for me had been harmful pharmaceutical drugs.
    "How fortunate for me that I found the Millen's Vital Heart Health for Life site. I ordered policosanol and within six months my HDL began improving. My last test, three months ago showed my HDL at 36, not ideal I realize, but for me the best it has ever been. Triglycerides and LDL were also within normal range, and my total cholesterol was 180.
    "I am so very thankful that Gene and Bernie Millen continue to offer what I consider life-saving advice and products for those of us who are desperately searching for alternatives to the "traditional" drugs prescribed by most physicians today.

    By: Janelle Carey, Savoy, Illinois

    Click here to try Vital Life Nutrionals Policosanol Extra Strength capsules (made with the same formula used in the clinical studies). On Sale Now. Save 40%.

    Thanks for joining us on the journey toVital Heart Health for Life!
    Gene Millen signature

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    Clinical Studies - References

  • Wikipedia indicates that policosanol clinical trials have shown mixed results.

  • Pub Med Policosanol Clinical Studies Confirm Benefits.
  • Am J Health Syst Pharm. 2024;60(11)




  • Valdes S., Arruzazabala M.L., Carbajal D., et al. (1996): Effect of policosanol on platelet aggregation in healthy volunteers. Intern. J.Clin. Pharmacol. Res. 16:67-72.


  • Canetti M., Morera M., Illnait J., et al. (1995): One year study on the effect of policosanol (5 mg-twice-a-day) on lipid profile in patients with type II hypercholesterolemia. Adv. Ther.12:245-254.

  • Canetti M., Morera M., Illnait J., et al. (1995): A two year study on the efficacy and tolerability of policosanol in patients with type II hypercholesterolemia. Intern. J. Clin. Pharmacol. Res. 15:159-165.

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    "I am so very thankful that Gene and Bernie Millen continue to offer what I consider life-saving advice, and products such as policosanol, for those of us who are desperately searching for alternatives to the "traditional" drugs prescribed by most physicians today."
    Janelle Carey, Savoy, Illinois


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